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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
11.52
Human Site:
Y42
Identified Species:
23.03
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
Y42
E
D
G
E
M
A
K
Y
V
Q
G
D
A
I
G
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
Y42
E
D
G
E
M
A
K
Y
V
Q
G
D
A
I
G
Dog
Lupus familis
XP_531626
735
82556
Y42
E
E
G
E
M
S
E
Y
L
Q
G
D
A
I
G
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
C43
D
G
E
M
N
R
F
C
Q
G
D
A
I
G
Y
Rat
Rattus norvegicus
P51556
727
82180
G42
E
M
N
K
Y
C
Q
G
D
E
I
G
Y
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
I80
A
E
L
P
D
D
F
I
E
H
L
F
T
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
A45
F
N
A
D
G
R
L
A
K
Y
R
H
G
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
S218
A
S
N
P
A
R
R
S
V
D
S
S
P
S
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
S102
V
R
A
K
F
S
E
S
L
S
G
R
M
A
G
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
D510
M
E
T
Y
L
D
V
D
M
P
E
D
L
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L41
V
A
A
L
V
G
I
L
T
I
A
Y
T
A
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
0
100
73.3
N.A.
0
13.3
N.A.
N.A.
0
N.A.
0
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
0
100
100
N.A.
6.6
40
N.A.
N.A.
6.6
N.A.
13.3
N.A.
13.3
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
25
0
9
17
0
9
0
0
9
9
25
17
0
% A
% Cys:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
9
% C
% Asp:
9
17
0
9
9
17
0
9
9
9
9
34
0
0
0
% D
% Glu:
34
25
9
25
0
0
17
0
9
9
9
0
0
9
0
% E
% Phe:
9
0
0
0
9
0
17
0
0
0
0
9
0
0
17
% F
% Gly:
0
9
25
0
9
9
0
9
0
9
34
9
9
9
42
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
9
% H
% Ile:
0
0
0
0
0
0
9
9
0
9
9
0
9
25
0
% I
% Lys:
0
0
0
17
0
0
17
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
9
0
9
9
17
0
9
0
9
9
0
% L
% Met:
9
9
0
9
25
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
9
17
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
17
0
0
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
9
25
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
25
9
0
0
0
9
9
0
0
9
% R
% Ser:
0
9
0
0
0
17
0
17
0
9
9
9
0
17
0
% S
% Thr:
0
0
9
0
0
0
0
0
9
0
0
0
17
0
0
% T
% Val:
17
0
0
0
9
0
9
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
0
25
0
9
0
9
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _